The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Jun. 07, 2018
Applicants:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Bayer Aktiengesellschaft, Leverkusen, DE;

Inventors:

Martina Delbeck, Heiligenhaus, DE;

Michael Hahn, Langenfeld, DE;

Thomas Müller, Langenfeld, DE;

Klemens Lustig, Wuppertal, DE;

Johanna Anlahr, Dortmund, DE;

Karl Collins, Düsseldorf, DE;

Janine Nicolai, Essen, DE;

Moritz Beck-Broichsitter, Darmstadt, DE;

Udo Albus, Florstadt, DE;

Doris Gehring, Kelkheim, DE;

Björn Rosenstein, Bad Soden-Salmünster, DE;

Hongkai Dang, Xi'an, CN;

Dehe Duan, Xi'an, CN;

Jianfei Yang, Xi'an, CN;

Denghui Chen, Wuhan, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61P 11/00 (2006.01); A61K 45/06 (2006.01); A61K 31/5513 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 11/00 (2018.01); A61K 45/06 (2013.01);
Abstract

The present application relates to novel imidazopyridinyl- or imidazopyrimidinyl-substituted, bridged 1,4-diazepane derivatives of formula (I), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring. Formula (I) in which the ring Q represents a bridged 1,4-diazepane cycle.


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