The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Oct. 09, 2017
Applicants:

Bayer Aktiengesellschaft, Leverkusen, DE;

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Anja Giese, Berlin, DE;

Jürgen Klar, Wuppertal, DE;

Alexander Helmut Michael Ehrmann, Cambridge, MA (US);

Jens Willwacher, Biberach an der Riß, DE;

David Engel, Wuppertal, DE;

Andre Philippe Dieskau, Wuppertal, DE;

Antje Kahnert, Wuppertal, DE;

Alexey Gromov, Erkrath, DE;

Carsten Schmeck, Mülheim, DE;

Niels Lindner, Wuppertal, DE;

Thomas Müller, Langenfeld, DE;

Anna Lena Andreevski, Solingen, DE;

Jan Dreher, Wuppertal, DE;

Karl Collins, Düsseldorf, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients.


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