The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Jul. 28, 2017
Applicant:
Hangzhou Solipharma Co., Ltd., Zhejiang, CN;
Inventors:
Xiaohong Sheng, Zhejiang, CN;
Xiaoxia Sheng, Zhejiang, CN;
Assignee:
Hangzhou Solipharma Co., Ltd., Zhejiang, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/30 (2006.01); C07C 57/15 (2006.01);
U.S. Cl.
CPC ...
C07D 213/30 (2013.01); C07C 57/15 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to a compound formed by entinostat as shown in formula (I) and acidic counterion. Compared with the known solid form of entinostat, the compound involved has advantages in terms of solubility, stability, etc. The present invention also relates to a crystalline form of the compound and a preparation method therefor, a pharmaceutical composition thereof and the use thereof in the preparation of a drug for preventing and/or treating a disease associated with differentiation or proliferation.