The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Apr. 11, 2018
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Jacob Hooker, Belmont, MA (US);
Changning Wang, Melrose, MA (US);
Martin Georg Strebl-Bantillo, Somerville, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/04 (2006.01); C07C 259/10 (2006.01);
U.S. Cl.
CPC ...
A61K 51/04 (2013.01); C07C 259/10 (2013.01); C07B 2200/05 (2013.01); C07C 2602/42 (2017.05); C07C 2603/74 (2017.05);
Abstract
Provided herein are compounds useful for binding to one or more histone deacetylase enzymes (HDACs). The present application further provides radiolabeled compounds useful as a radiotracer for position emission tomography imaging of HDAC. Methods for prepared unlabeled and labeled compounds, diagnostic methods, and methods of treating diseases associated HDAC are also provided.