The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Jun. 12, 2015
Applicants:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Yasuhiro Ikeda, Rochester, MN (US);

Claire A. Schreiber, Rochester, MN (US);

Toshie Sakuma, Rochester, MN (US);

Sara J. Holditch, Rochester, MN (US);

Kazunori Koide, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/864 (2006.01); A61K 48/00 (2006.01); C12N 15/09 (2006.01); C12N 15/86 (2006.01); A61K 31/5377 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/00 (2013.01); A61K 31/5377 (2013.01); A61K 48/0083 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C12N 2750/14143 (2013.01);
Abstract

This document relates to methods and materials for increasing viral vector infectivity. For example, methods and materials for using spliceosome inhibitors (e.g., U2 snRNP spliceosome inhibitors such as meayamycin B or pladienolide derivative E7107) to increase viral vector (e.g., adeno-associated virus-based vector) infectivity are provided.


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