The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Apr. 16, 2019
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Martin Zillmann, Shrewsbury, MA (US);
Alexandra Krog, Bodenheim, DE;
Raphael Guebeli, Darmstadt, DE;
Tanja Henzler, Mannheim, DE;
Christian Hildebrandt, Heppenheim, DE;
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/26 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01);
U.S. Cl.
CPC ...
A61K 47/26 (2013.01); A61K 9/0095 (2013.01); A61K 9/19 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01);
Abstract
The present invention relates to compositions of highly concentrated protein formulations showing reduced viscosity. The contained proteins in the prepared formulations are stabilized against aggregation and denaturation and are thus sufficiently storage-stable until administration to the patient.