The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Oct. 14, 2016
President and Fellows of Harvard College, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Arlene H. Sharpe, Brookline, MA (US);
Gordon J. Freeman, Brookline, MA (US);
Loise M. Francisco, Belmont, MA (US);
Peter T. Sage, Brookline, MA (US);
Sun J. Lee, Statesboro, GA (US);
Scott B. Lovitch, Somerville, MA (US);
Vikram R. Juneja, Boston, MA (US);
Catherine L. Tan, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
The present invention is based, in part, on the identification of methods of modulating PD-1 expression and/or activity in regulatory T cells (Tregs) to thereby regulate effector immune responses in effector T cells (Teffs).