The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Jun. 21, 2019
Applicant:

Zx Pharma, Llc, Boca Raton, FL (US);

Inventors:

Syed M. Shah, Boca Raton, FL (US);

Fred Hassan, Boca Raton, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/045 (2006.01); A61K 36/82 (2006.01); A61K 36/534 (2006.01); A61K 36/23 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5057 (2013.01); A61K 9/0053 (2013.01); A61K 9/2054 (2013.01); A61K 9/2081 (2013.01); A61K 9/2095 (2013.01); A61K 9/4808 (2013.01); A61K 9/4833 (2013.01); A61K 9/4866 (2013.01); A61K 9/5026 (2013.01); A61K 9/5073 (2013.01); A61K 9/5089 (2013.01); A61K 31/045 (2013.01); A61K 36/23 (2013.01); A61K 36/534 (2013.01); A61K 36/82 (2013.01);
Abstract

A method of making an L-menthol dosage form includes forming a wet granulation including an L-menthol source and at least one pharmaceutical excipient. The wet granulation is extruded into an extrudate and the extrudate is cut into individual core pieces. The individual core pieces are spheronized into individual spheronized cores and the individual spheronized cores are dried to form dried individual spheronized cores. The dried individual spheronized cores are spray coated with a liquid proteinaceous material that forms a film of a proteinaceous material over the dried individual spheronized cores. The film of proteinaceous material is dried over the dried individual spheronized cores to form individual subcoated cores. An enteric coating is applied and dried over the individual subcoated cores to form a plurality of individual enteric coated cores.


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