The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Mar. 08, 2019
Applicant:
Centre National DE LA Recherche Scientifique, Paris, FR;
Inventor:
Domenico Maiorano, Saint Martin de Londres, FR;
Assignee:
Centre National de la Recherche Scientifique, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12Q 1/6886 (2018.01); C07K 16/18 (2006.01); A61K 31/255 (2006.01); A61K 31/4745 (2006.01); A61K 31/555 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); C12N 9/00 (2006.01); C07K 16/40 (2006.01); A61K 33/243 (2019.01); A61K 31/381 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/255 (2013.01); A61K 31/381 (2013.01); A61K 31/4745 (2013.01); A61K 31/555 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 33/243 (2019.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); C12N 9/93 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); C12Y 203/02 (2013.01); C12Y 603/02 (2013.01); G01N 33/57496 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/9108 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention relates to the use of an inhibitor of Rad18 expression or activity, in treating a tumor or in sensitizing a patient affected with a tumor, to a treatment with an antineoplastic agent that is a DNA damaging chemotherapeutic agent so to both reduce the self renewal of cancer stem cells and increase the DNA damage response thus boosting apoptotic cell death.
Maiorano, Domenico. (2021). Use of rad18 inhibitors in the treatment of tumors (U.S. Patent No. 11203757). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11203757
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile