The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Jul. 09, 2018
Applicants:
Eli Lilly and Company, Indianapolis, IN (US);
Zymeworks Inc., Vancouver, CA;
Inventors:
Michael Dewain Kalos, Brooklyn, NY (US);
Yiwen Li, Woodcliff Lake, NJ (US);
Dale Lincoln Ludwig, Rockaway, NJ (US);
Yang Shen, Scarsdale, NJ (US);
Igor Edmondo Paolo D'Angelo, Anmore, CA;
Gregory D Plowman, New York, NY (US);
Assignees:
Eli Lilly and Company, Indianapolis, IN (US);
Zymeworks Inc., Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2827 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/524 (2013.01); C07K 2317/64 (2013.01);
Abstract
The present invention relates to antibodies that are heterodimeric and bind human PD-L1 and human PD-1, and may be useful for treating cancer alone and in combination with chemotherapy and other cancer therapeutics.