The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Jul. 29, 2016
Applicant:
Glaxosmithkline Intellectual Property Development Limited, Brentford, GB;
Inventors:
Valeriu Damian, King of Prussia, PA (US);
Austin Keith Doyle, Stevenage, GB;
Laura Maria Halo, Stevenage, GB;
Emma R. Harding, Stevenage, GB;
Xuan Hong, King of Prussia, PA (US);
Alan Peter Lewis, Stevenage, GB;
Mark Uden, Stevenage, GB;
Assignee:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, Brentford, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); C07K 16/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); A61K 2039/54 (2013.01); C07K 2317/567 (2013.01); C07K 2317/94 (2013.01); C40B 30/04 (2013.01);
Abstract
The present invention relates to methods of selecting, screening, engineering, making and modifying antibodies that have improved bioavailability upon subcutaneous administration to a human. Antibodies and variant antibodies with improved bioavailability upon subcutaneous administration to a human are also described.