The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Dec. 18, 2014
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Assignee:
Novartis AG, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C12N 15/113 (2013.01); C07K 2317/14 (2013.01); C12N 2310/14 (2013.01); C12N 2510/02 (2013.01); C12N 2511/00 (2013.01);
Abstract
The disclosure pertains to novel eukaryotic cell suitable for recombinant production of a product of interest, wherein the effect of the expression product of an endogenous gene C12orf35 is impaired in said cell, thereby increasing their productivity when recombinantly expressing a polypeptide of interest. Furthermore, the present disclosure provides associated technologies wherein such host cells are used in recombinant production technologies.