The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Aug. 23, 2019
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Tracy S. Mitchell, Andover, MA (US);
Michael L. Gosselin, Boston, MA (US);
Dasa Lipovsek, Pepperell, MA (US);
Rex Parker, Titusville, NJ (US);
Ray Camphausen, Wayland, MA (US);
Jonathan H. Davis, Madison, WI (US);
David Fabrizio, South Hamilton, MA (US);
Assignee:
BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12P 21/06 (2006.01); C12N 15/87 (2006.01); C12N 5/20 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C07K 14/78 (2006.01); A61K 47/64 (2017.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 47/64 (2017.08); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/70 (2013.01);
Abstract
The present invention relates to polypeptides which include tenth fibronectin type III domains (Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-bindingFn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.