The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 21, 2021

Filed:

Dec. 14, 2017
Applicant:

Acceleron Pharma Inc., Cambridge, MA (US);

Inventors:

Ravindra Kumar, Acton, MA (US);

Rajasekhar Naga Venkata Sai Suragani, Norwood, MA (US);

Assignee:

ACCELERON PHARMA INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/495 (2006.01); C07K 14/71 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 14/495 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07K 14/71 (2013.01); C07K 2319/30 (2013.01);
Abstract

In part, the present disclosure relates methods for treating, preventing, or reducing the severity of a myeloproliferative disorder (e.g., polycythemia vera, essential thrombocythemia, and myelofibrosis) or one or more complications of a myeloproliferative disorder. The present disclosure further relates methods for treating, preventing, or reducing the severity of a Janus kinase-associated disorder or one or more complications of a Janus kinase-associated disorder. In certain aspects the disclosure provides TβRII antagonists for treating, preventing, or reducing the severity of a myeloproliferative disorder (e.g., polycythemia vera, essential thrombocythemia, and myelofibrosis) or a Janus kinase-associated disorder or one or more complications of a myeloproliferative disorder or a Janus kinase-associated disorder.


Find Patent Forward Citations

Loading…