The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 21, 2021

Filed:

Jul. 28, 2020
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Badry Bursulaya, Escondido, CA (US);

Andreas Fisch, Basel, CH;

James Paul Lajiness, San Diego, CA (US);

Rainer Machauer, Freiburg, DE;

Swapnil Malekar, Emeryville, CA (US);

Hank Michael James Petrassi, San Diego, CA (US);

Farshad Ramazani, Basel, CH;

Anne-Catherine Remond, Bartenheim, FR;

Thomas Ullrich, Bottmingen, CH;

Peggy Usselmann, Wahlbach, FR;

Eric Vangrevelinghe, Saint-Louis, FR;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 9/19 (2006.01); A61P 21/00 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 31/437 (2006.01); A61K 31/496 (2006.01); A61K 31/538 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 9/0019 (2013.01); A61K 9/5031 (2013.01); A61K 31/437 (2013.01); A61K 31/496 (2013.01); A61K 31/538 (2013.01); A61P 21/00 (2018.01);
Abstract

The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.


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