The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 21, 2021

Filed:

Mar. 11, 2019
Applicants:

The University of Memphis Research Foundation, Memphis, TN (US);

The University of Tennessee Research Foundation, Memphis, TN (US);

Inventors:

Gary L. Bowlin, Memphis, TN (US);

Allison E. Fetz, Memphis, TN (US);

Marko Z. Radic, Memphis, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61L 27/56 (2006.01); A61P 29/00 (2006.01); C08L 67/04 (2006.01); C08G 63/06 (2006.01); D01F 6/62 (2006.01); D01D 5/00 (2006.01); D01F 1/10 (2006.01); C08K 5/29 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61P 29/00 (2018.01); C08G 63/06 (2013.01); D01D 5/0007 (2013.01); D01F 1/10 (2013.01); A61L 2300/204 (2013.01); A61L 2300/41 (2013.01); A61L 2300/434 (2013.01); C08K 5/29 (2013.01); C08L 67/04 (2013.01); D01F 6/625 (2013.01);
Abstract

As described below, the present invention features compositions and methods for inhibiting inflammation in connection with an acellular template (e.g., an electrospun template). In one embodiment, the template is impregnated with an agent (e.g., N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide (Cl-amidine)) that inhibits a peptidylarginine deaminase (e.g., PAD4).


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