The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Nov. 13, 2019
Applicant:
Arch Oncology, Inc., Brisbane, CA (US);
Inventors:
Robyn Puro, St. Louis, MO (US);
Ronald R. Hiebsch, St. Louis, MO (US);
Benjamin J. Capoccia, St. Louis, MO (US);
Gabriela Andrejeva, St. Louis, MO (US);
Juan C. Almagro, Cambridge, MA (US);
Daniel S. Pereira, San Diego, CA (US);
Assignee:
Arch Oncology, Inc., Brisbane, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 9/0019 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract
Anti-SIRPα monoclonal antibodies (anti-SIRPα mAbs), including multispecific SIRPα antibodies, are provided with distinct functional profiles as are related compositions and methods of using anti-SIRPα mAbs as therapeutics for the prevention and treatment of solid and hematological cancers. Also provided are amino acid sequences of exemplary anti-SIRPα monoclonal antibodies.