The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Sep. 25, 2015
Nanyang Technological University, Singapore, SG;
National Skin Center (S) Pte Ltd, Singapore, SG;
Sierin Lim, Singapore, SG;
Sathyamoorthy Bhaskar, Singapore, SG;
Steven Thng, Singapore, SG;
Ambili Kuniyil, Singapore, SG;
Sarker Mridul, Singapore, SG;
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, SG;
NATIONAL SKIN CENTER (S) PTE LTD, Singapore, SG;
Abstract
The present invention relates to protein nanocages comprising a melanocyte-targeting moiety and pharmaceutical compositions comprising the protein cages as well as methods for treating or diagnosing hyperpigmentation disorders or other melanocyte-related disorders using the protein nanocages or pharmaceutical compositions. In the preferred embodiment, the protein nanocage is composed ofE2 protein of pyruvate dehydrogenase multi-enzyme complex (E2), with a skin penetrating and cell permeating SPACE moiety, and a melanocyte-targeting moiety of alpha melanocyte stimulating hormone.