The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2021
Filed:
Oct. 12, 2017
Applicant:
Georgetown University, Washington, DC (US);
Inventors:
Aykut Üren, Rockville, MD (US);
Haydar Celik, Potomac, MD (US);
Jeffrey A. Toretsky, Silver Spring, MD (US);
Assignee:
GEORGETOWN UNIVERSITY, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); A61P 37/06 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 9/0019 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01);
Abstract
Provided herein are methods of treating a bone or connective tissue cancer in a subject. The methods comprise administering to the subject an effective amount of a CD99 inhibitor, wherein the CD99 inhibitor is a compound having the formula wherein R, each of which may be the same or different, is hydrogen, or a protecting group; wherein Z is selected from the group consisting of F, Cl and Br; wherein X is H or F; and pharmaceutically acceptable salts thereof.