The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2021

Filed:

Aug. 28, 2020
Applicant:

Labcyte Inc., San Jose, CA (US);

Inventors:

Jennifer M. Hardee, San Jose, CA (US);

Richard N. Ellson, San Jose, CA (US);

Richard G. Stearns, San Jose, CA (US);

Babur Hadimioglu, San Jose, CA (US);

Joseph D. Olechno, San Jose, CA (US);

Marsha N. Blauwkamp, San Jose, CA (US);

Assignee:

LABCYTE INC., San Jose, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/64 (2006.01); C12N 15/87 (2006.01); A61N 7/00 (2006.01); C12N 9/22 (2006.01); C12N 13/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/64 (2013.01); A61N 7/00 (2013.01); C12N 9/22 (2013.01); C12N 13/00 (2013.01); C12N 15/11 (2013.01); C12N 15/87 (2013.01); A61N 2007/0039 (2013.01); A61N 2007/0073 (2013.01); C12N 2310/20 (2017.05);
Abstract

A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.


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