The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2021
Filed:
Jun. 14, 2018
Pfizer Inc., New York, NY (US);
Elizabeth Mary Beck, Oxford, GB;
Michael Aaron Brodney, Newton, MA (US);
Matthew Frank Brown, Stonington, CT (US);
Christopher Ryan Butler, Canton, MA (US);
Adam Matthew Gilbert, Guilford, CT (US);
Erik Alphie Lachapelle, Uncasville, CT (US);
Laura Ann McAllister, Arlington, MA (US);
Daniel Paul Uccello, Colchester, CT (US);
Lei Zhang, Auburndale, MA (US);
PFIZER INC., New York, NY (US);
Abstract
The present invention provides, in part, compounds of Formula I, or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: (R)a, (R)b, (R)c, L, A, and E are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.