The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2021

Filed:

Nov. 18, 2016
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

Charite—universitaetsmedizin Berlin, Berlin, DE;

Inventors:

Christine A. Cezar, Cambridge, MA (US);

Conor J. Walsh, Cambridge, MA (US);

David J. Mooney, Sudbury, MA (US);

Ellen T. Roche, Galway, IE;

Herman H. Vandenburgh, Providence, RI (US);

Georg N. Duda, Berlin, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/04 (2006.01); A61L 27/56 (2006.01); A61L 27/14 (2006.01);
U.S. Cl.
CPC ...
A61L 27/042 (2013.01); A61L 27/14 (2013.01); A61L 27/56 (2013.01); A61L 2400/06 (2013.01); A61L 2430/30 (2013.01);
Abstract

The present invention provides methods and compositions for promoting regeneration of a tissue, methods for preventing or reducing inflammation of a tissue, methods for preventing or reducing fibrosis of a tissue, methods for increasing a mass of a tissue, methods for increasing a level of oxygen available to a tissue, methods for increasing a rate of metabolic waste removal from a tissue, methods for increasing blood perfusion to a tissue, and methods of treating severe muscle tissue damage in a subject in need thereof by contacting the tissue with a composition that is suitable for applying cyclic mechanical compression to the tissue.


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