The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2021
Filed:
Feb. 17, 2017
Applicant:
Wisconsin Alumni Research Foundation (Warf), Madison, WI (US);
Inventors:
Yoshihiro Kawaoka, Middleton, WI (US);
Gabriele Neumann, Madison, WI (US);
Jihui Ping, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation (WARF), Madison, WI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5258 (2013.01); C12N 2760/16023 (2013.01); C12N 2760/16071 (2013.01); C12N 2760/16221 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16251 (2013.01);
Abstract
The invention provides a composition useful to prepare high titer influenza B viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza B virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs.