The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2021

Filed:

May. 18, 2017
Applicant:

Oxford University Innovation Limited, Oxford, GB;

Inventor:

Arturo Reyes-Sandoval, Headington, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); A61K 39/285 (2006.01); A61K 39/29 (2006.01); A61K 39/235 (2006.01); A61P 33/06 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61K 39/235 (2013.01); A61K 39/285 (2013.01); A61K 39/29 (2013.01); A61K 39/39 (2013.01); A61P 33/06 (2018.01); A61K 2039/5258 (2013.01); A61K 2039/6075 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to particles, particularly virus-like particles (VLPs), comprising fusion polypeptides comprising selected repeat units derived from the repeating regions of Type I and Type II circumsporozoite proteins (CSP) of(Pv), together with an amino acid sequence derived from the C-terminal PvCSP sequence. In some embodiments, the fusion polypeptide additionally comprises an amino acid sequence derived from the N-terminal PvCSP sequence and/or a surface antigen polypeptide derived from Hepatitis B virus (HBV-S). The invention also relates to nucleotide sequences coding for such fusion polypeptides, vectors and plasmids comprising such nucleotide sequences, and host cells comprising such vectors and plasmids. The invention additionally relates to compositions, particularly vaccine compositions, comprising the fusion polypeptides or VLPs for use as vaccines for the prevention of malaria.


Find Patent Forward Citations

Reyes-Sandoval, Arturo. (2021). Vaccines (U.S. Patent No. 11197920). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11197920

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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