The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2021

Filed:

Nov. 04, 2016
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Saul J. Priceman, Duarte, CA (US);

Stephen J. Forman, Duarte, CA (US);

Christine E. Brown, Duarte, CA (US);

Assignee:

City of Hope, Duarte, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); C07K 16/32 (2006.01); A61K 39/00 (2006.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C12N 15/86 (2006.01); C07K 14/71 (2006.01); C12N 5/0783 (2010.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001106 (2018.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70503 (2013.01); C07K 14/70521 (2013.01); C07K 14/71 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C12N 5/0636 (2013.01); C12N 15/86 (2013.01); A61K 35/17 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C07K 2317/524 (2013.01); C07K 2317/622 (2013.01); C07K 2317/71 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 2740/16043 (2013.01); C12N 2830/15 (2013.01);
Abstract

Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain targeted to HER2, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.


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