The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2021
Filed:
Dec. 12, 2017
Applicant:
New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery, New York, NY (US);
Inventor:
Franck Barrat, New York, NY (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 38/19 (2006.01); A61P 17/00 (2006.01); A61K 45/06 (2006.01); A61P 37/00 (2006.01); A61P 35/00 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 31/00 (2013.01); A61K 38/195 (2013.01); A61K 45/06 (2013.01); A61P 17/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01);
Abstract
The current invention is related to the prevention and treatment of diseases including cancer, autoimmune disease, and infectious disease using CXC chemokines and the receptors to which they agonize. It has been found that certain chemokines, including CXCL4, CXCL9, CXCL10, and CXCL12 have various effects on toll-like receptors in various cell types and these can be utilized for disease treatment and prevention.