The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2021
Filed:
Dec. 17, 2019
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventors:
Jordan D. Miller, Rochester, MN (US);
Bin Zhang, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/635 (2006.01); A61K 31/197 (2006.01); A61K 31/416 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/635 (2013.01); A61K 31/197 (2013.01); A61K 31/416 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract
This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sGC agonists or a combination of sGC agonists and PDE5A inhibitors to reduce calcification of heart valves and/or vessels or to slow progression of aortic sclerosis to calcific aortic valve stenosis are provided.