The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2021

Filed:

Nov. 19, 2015
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Shyam B. Karki, Hillsborough, NJ (US);

Peter Zawaneh, Brookline, MA (US);

Cheuk-Yui Leung, Acton, MA (US);

Kalyan Vasudevan, Cambridge, MA (US);

Yiqing Lin, Lexington, MA (US);

Jin Xu, Waltham, MA (US);

Andrea Trementozzi, Sherborn, MA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/225 (2006.01); A61P 37/00 (2006.01); A61K 9/16 (2006.01); A61K 9/24 (2006.01); A61K 9/28 (2006.01); A61K 9/50 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/225 (2013.01); A61K 9/1676 (2013.01); A61K 9/209 (2013.01); A61K 9/288 (2013.01); A61K 9/2826 (2013.01); A61K 9/2846 (2013.01); A61K 9/2853 (2013.01); A61K 9/2866 (2013.01); A61K 9/2873 (2013.01); A61K 9/2886 (2013.01); A61K 9/5078 (2013.01); A61P 25/00 (2018.01); A61P 37/00 (2018.01);
Abstract

The present invention provides novel pharmaceutical compositions of dimethyl fumarate. The pharmaceutical compositions of the present invention are in the form of a bead and comprise (i) an inert core; (ii) a first layer surrounding the inert core, wherein the first layer comprises dimethyl fumarate; and (iii) an enteric coating surrounding the first layer. Also provided are pharmaceutical compositions in the form of a bead comprising a core and an enteric coating surrounding the core, wherein the core comprises dimethyl fumarate. Methods of using the pharmaceutical compositions of the present invention for treating multiple sclerosis are also included.


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