The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

May. 24, 2018
Applicants:

The Regents of the University of California, Oakland, CA (US);

Ludwig Institute for Cancer Research Ltd, Zurich, CH;

Inventors:

Paul Mischel, Los Angeles, CA (US);

Prashant Mali, San Diego, CA (US);

Vineet Bafna, San Diego, CA (US);

Kristen Turner, San Diego, CA (US);

Viraj Deshpande, San Diego, CA (US);

Doruk Beyter, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6841 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6841 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01);
Abstract

Provided herein are, inter alia, methods and compositions to detect, monitor and treat cancer, wherein the cancer includes amplified extrachromosomal oncogenes. The methods are useful for personalized treatment and exploit differential expression of amplified extrachromosomal oncogenes in cancer cells versus healthy cells.


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