The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

May. 29, 2020
Applicant:

Zymergen Inc., Emeryville, CA (US);

Inventors:

Grayson Wawrzyn, Oakland, CA (US);

Christine Roche, Emeryville, CA (US);

Patrick J. Westfall, Emeryville, CA (US);

Warren Lau, Emeryville, CA (US);

Savita Ganesan, Emeryville, CA (US);

Fern R. McSorley, Emeryville, CA (US);

Zach Serber, Emeryville, CA (US);

Assignee:

ZYMERGEN INC., Emeryville, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/06 (2006.01); C12N 9/00 (2006.01); C12N 15/52 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12P 17/06 (2013.01); C12N 9/001 (2013.01); C12N 9/0006 (2013.01); C12N 15/52 (2013.01); C12Y 101/01324 (2015.07); C12Y 103/01 (2013.01);
Abstract

The present disclosure provides isolated nepetalactone oxidoreductase polypeptides (NORs), nepetalactol synthases (NEPSs), and related polynucleotides, engineered host cells, and cultures, as well as methods for producing NORs and NEPSs, and for using them to produce nepetalactol, nepetalactone, and dihydronepetalactone. The present disclosure also provides methods for engineering cells (e.g., microbial cells) to produce nepetalactone from a fermentation substrate such as glucose, as well as engineered cells having this capability and related cultures and methods for producing nepetalactone.


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