The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

Mar. 23, 2017
Applicant:

Universiteit Gent, Ghent, BE;

Inventors:

Elena Diana Giol, Brasov, RO;

Peter Dubruel, Ghent, BE;

Sandra Van Vlierberghe, Sint-Niklaas, BE;

Assignee:

UNIVERSITEIT GENT, Ghent, BE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08G 63/183 (2006.01); A61L 27/18 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); C08G 63/81 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12M 1/32 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C08G 63/183 (2013.01); A61L 27/18 (2013.01); A61L 27/3808 (2013.01); A61L 27/3895 (2013.01); A61L 27/507 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); C08G 63/81 (2013.01); C12M 23/12 (2013.01); C12M 23/20 (2013.01); C12M 47/04 (2013.01); C12N 5/0068 (2013.01); C12N 5/069 (2013.01); A61L 2300/64 (2013.01); C08G 2230/00 (2013.01); C12N 2533/30 (2013.01);
Abstract

The present invention relates to poly(alkylene terephthalate) polyesters having long poly-methylene segments and their use in a wide variety of applications. Particularly, said PAT polyesters are used in biotechnological or biomedical applications, wherein the extent of cell adhesion, cell growth or cell interaction, in particular endothelial cells, depends on the odd or even number of carbon atoms in the aliphatic segments. Also provided are methods for the preparation of poly(alkylene terephthalates) (PAT) having long poly-methylene segments, wherein the bifunctional monomers, in particular terephthalic acid (or a derivative thereof) and an aliphatic diol, are dissolved in a solvent and the polycondensation reaction takes place in solution.


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