The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Sep. 29, 2016
Applicant:
Medimmune Limited, Cambridge, GB;
Inventors:
Elaine M. Hurt, Gaithersburg, MD (US);
Ralph Minter, Cambridge, GB;
Steven Rust, Cambridge, GB;
Alan Sandercock, Cambridge, GB;
Sotirios Karathanasis, Gaithersburg, MD (US);
Assignee:
MedImmune Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12N 5/095 (2010.01); G01N 33/574 (2006.01); C12Q 1/25 (2006.01); A61K 31/713 (2006.01); A61K 31/704 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 31/704 (2013.01); A61K 31/713 (2013.01); C07K 16/2851 (2013.01); C07K 16/30 (2013.01); C12N 5/0695 (2013.01); C12Q 1/25 (2013.01); G01N 33/574 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C07K 2318/00 (2013.01);
Abstract
The disclosure generally provides compositions and methods that are useful in the treatment of cancer. More specifically, the methods and compositions may be used to detect, quantify, inhibit, kill, differentiate, or eliminate cancer stem cells (CSCs) and may be used in the treatment of cancers associated with CSCs, and particularly cancers and CSCs that express LOX1.