The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Oct. 11, 2018
Applicant:
Bioverativ Usa Inc., Waltham, MA (US);
Inventors:
Sandip Panicker, South San Francisco, CA (US);
Stephen Moore, South San Francisco, CA (US);
Pavel A. Nikitin, South San Francisco, CA (US);
Tony Byun, South San Francisco, CA (US);
Graham Parry, South San Francisco, CA (US);
Assignee:
Bioverativ USA Inc., Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure provides methods of inducing a complement activity on a surface of a cell comprising contacting the cell with an effective amount of an anti-Factor B antibody, wherein the anti-Factor B antibody inhibits dissociation of a C3bBb complex into a Factor Bb and a C3b.