The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Mar. 02, 2018
Auckland Uniservices Limited, Auckland, NZ;
Guangzhou Institute of Biomedicine and Health, Guangdong, CN;
Adam Vorn Patterson, Auckland, NZ;
Jeffrey Bruce Smaill, Auckland, NZ;
Amir Ashoorzadeh, Auckland, NZ;
Christopher Paul Guise, Auckland, NZ;
Christopher John Squire, Auckland, NZ;
Swarnalatha Akuratiya Gamage, Auckland, NZ;
Maria Rosaria Abbattista, Auckland, NZ;
Matthew Roy Bull, Auckland, NZ;
Angus Cheverton Grey, Auckland, NZ;
Xueqiang Li, Guangdong, CN;
Ke Ding, Guangdong, CN;
Xiaomei Ren, Guangdong, CN;
Shuang Jiang, Guangdong, CN;
Zhengchao Tu, Guangdong, CN;
AUCKLAND UNISERVICES LIMITED, Auckland, NZ;
GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, Guangdong, CN;
Abstract
Fibroblast Growth Factor Receptor kinase inhibitors and prodrugs thereof of Formula (I) and their use for the treatment of hyper-proliferative diseases such as retinopathy, psoriasis, rheumatoid arthritis, osteoarthritis, septic arthritis, tumour metastasis, periodontal disease, corral ulceration, proteinuria, coronary thrombosis from atherosclerotic plaque, aneurismal aorta, dystrophobic epidermolysis bullosa, degenerative cartilage loss following traumatic joint injury, osteopenias mediated by MMP activity, tempero mandibular joint disease, and demyelating disease of the nervous system.