The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
May. 11, 2018
Korea Research Institute of Chemical Technology, Daejeon, KR;
Jong Yeon Hwang, Jeollabuk-do, KR;
Jae Du Ha, Daejeon, KR;
Sung Yun Cho, Daejeon, KR;
Pil Ho Kim, Daejeon, KR;
Chang Soo Yun, Daejeon, KR;
Chi Hoon Park, Daejeon, KR;
Chong Ock Lee, Seoul, KR;
Sang Un Choi, Daejeon, KR;
Joo Youn Lee, Daejeon, KR;
Sunjoo Ahn, Daejeon, KR;
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, Daejeon, KR;
Abstract
The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.