The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

Jul. 11, 2018
Applicant:

Sandoz Ag, Basel, CH;

Inventors:

Hannes Lengauer, Kundl, AT;

Arthur Pichler, Kundl, AT;

Renate Margreiter, Kundl, AT;

Thomas Gelbrich, Innsbruck, AT;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/26 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); C07D 207/16 (2006.01);
U.S. Cl.
CPC ...
C07D 217/26 (2013.01); A61K 9/0053 (2013.01); A61K 47/02 (2013.01); C07D 207/16 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to a co-crystal of roxadustat with L-proline and to a process for its preparation. Furthermore, the invention relates to a pharmaceutical composition comprising said roxadustat L-proline co-crystal, at least one pharmaceutically acceptable excipient and optionally at least one photostabilizing agent. The pharmaceutical composition of the present invention can be used as a medicament, in particular for the treatment and/or prevention of anemia in patients with end-stage renal disease (ESRD) and/or chronic kidney disease (CKD).


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