The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
May. 23, 2017
Applicant:
Portland State University, Portland, OR (US);
Inventors:
Robert M Strongin, Portland, OR (US);
Martha Sibrian-Vazquez, Portland, OR (US);
Lei Wang, Camas, WA (US);
Jorge O. Escobedo Cordova, Portland, OR (US);
Mark A. Lowry, Portland, OR (US);
Assignee:
Portland State University, Portland, OR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); A61K 49/00 (2006.01); A61K 9/00 (2006.01); C07D 311/86 (2006.01); C07D 491/16 (2006.01); C09B 11/16 (2006.01); C09B 11/22 (2006.01); C09B 11/24 (2006.01); C09K 11/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0043 (2013.01); A61K 9/0012 (2013.01); A61K 49/006 (2013.01); C07D 311/86 (2013.01); C07D 491/16 (2013.01); C09B 11/16 (2013.01); C09B 11/22 (2013.01); C09B 11/24 (2013.01); C09K 11/06 (2013.01); C09K 2211/1007 (2013.01); C09K 2211/1018 (2013.01);
Abstract
Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Embodiments of the disclosed probes are useful for pancreatic cancer detection, therapeutic monitoring, and/or image-guided surgery.