The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Jun. 30, 2017
Applicant:
Arbutus Biopharma Corporation, Burnaby, CA;
Inventors:
Michael J. Abrams, Custer, WA (US);
James Heyes, Vancouver, CA;
Adam Judge, Bainbridge Island, WA (US);
Kieu Mong Lam, Richmond, CA;
Lorne Ralph Palmer, Vancouver, CA;
Stephen P. Reid, Vancouver, CA;
Edward D. Yaworski, Maple Ridge, CA;
Assignee:
ARBUTUS BIOPHARMA CORPORATION, Burnaby, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 9/51 (2006.01); A61K 31/573 (2006.01); A61K 31/58 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 47/69 (2017.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 48/0083 (2013.01); A61K 9/0019 (2013.01); A61K 9/5123 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); A61K 47/544 (2017.08); A61K 47/60 (2017.08); A61K 47/6909 (2017.08); A61K 47/6911 (2017.08); B82Y 5/00 (2013.01); C12N 15/111 (2013.01); C12N 2320/32 (2013.01);
Abstract
The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.