The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Jul. 08, 2019
Applicant:
Vascular Biogenics Ltd., Modiin, IL;
Inventors:
Andrea Rachel Leubitz, Efrat, IL;
Naamit Sher, Rechovot, IL;
Erez Feige, Hemed, IL;
Eyal Breitbart, Hashmonaim, IL;
Assignee:
Vascular Biogenics Ltd., Modiin, IL;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01); C07K 14/705 (2006.01); C07K 16/22 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 38/1793 (2013.01); A61K 38/191 (2013.01); A61K 39/3955 (2013.01); C07K 14/70578 (2013.01); C07K 16/22 (2013.01); C12N 2710/10343 (2013.01);
Abstract
The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and administering the VEGF antagonist.