The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2021
Filed:
Apr. 04, 2018
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventors:
Miguel A. Munoz Alia, Rochester, MN (US);
Stephen James Russell, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/705 (2006.01); C12N 7/00 (2006.01); C07K 14/435 (2006.01); C12N 15/00 (2006.01); A61K 39/165 (2006.01);
U.S. Cl.
CPC ...
A61K 39/165 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/55 (2013.01); C12N 2710/10021 (2013.01); C12N 2760/18421 (2013.01); C12N 2760/18422 (2013.01); C12N 2760/18434 (2013.01);
Abstract
This document relates to methods and materials for making and using viruses (e.g., measles viruses or adenoviruses) having a reduced susceptibility to antibody neutralization (e.g., antibody neutralization by serum from measles virus vaccines). For example, recombinant morbilliviruses (e.g., recombinant measles viruses) having a modified H gene and a modified F gene, as well as methods of using a recombinant virus are provided.