The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

Jun. 25, 2004
Applicants:

Anthony J. Kihm, Princeton, NJ (US);

Agnieszka Seyda, New Brunswick, NJ (US);

Sridevi Dhanaraj, Raritan, NJ (US);

Ziwei Wang, Monroe, NJ (US);

Alexander M. Harmon, Clinton, NJ (US);

Ian Ross Harris, Belle Mead, NJ (US);

Darin J. Messina, Somerville, NJ (US);

Sanjay Mistry, Bedminster, NJ (US);

Anna Gosiewska, Skillman, NJ (US);

Chin-feng Yi, Hillsborough, NJ (US);

Inventors:

Anthony J. Kihm, Princeton, NJ (US);

Agnieszka Seyda, New Brunswick, NJ (US);

Sridevi Dhanaraj, Raritan, NJ (US);

Ziwei Wang, Monroe, NJ (US);

Alexander M. Harmon, Clinton, NJ (US);

Ian Ross Harris, Belle Mead, NJ (US);

Darin J. Messina, Somerville, NJ (US);

Sanjay Mistry, Bedminster, NJ (US);

Anna Gosiewska, Skillman, NJ (US);

Chin-Feng Yi, Hillsborough, NJ (US);

Assignee:

Depuy Synthes Products, Inc., Raynham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 35/51 (2015.01); C12N 5/074 (2010.01); C12N 5/073 (2010.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/27 (2006.01); C12N 5/0735 (2010.01); A61K 35/50 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/51 (2013.01); A61K 35/50 (2013.01); A61K 38/18 (2013.01); A61K 38/185 (2013.01); A61K 38/1808 (2013.01); A61K 38/1825 (2013.01); A61K 38/1833 (2013.01); A61K 38/1841 (2013.01); A61K 38/1858 (2013.01); A61K 38/1866 (2013.01); A61K 38/1891 (2013.01); A61K 38/19 (2013.01); A61K 38/204 (2013.01); A61K 38/2053 (2013.01); A61K 38/27 (2013.01); C12N 5/0605 (2013.01); C12N 5/0606 (2013.01); C12N 5/0607 (2013.01); A61K 35/12 (2013.01); C12N 2500/32 (2013.01); C12N 2500/34 (2013.01); C12N 2500/44 (2013.01); C12N 2500/90 (2013.01); C12N 2500/95 (2013.01); C12N 2501/12 (2013.01); C12N 2501/21 (2013.01); C12N 2501/23 (2013.01); C12N 2502/02 (2013.01); C12N 2506/02 (2013.01); C12N 2506/03 (2013.01); C12N 2509/00 (2013.01); C12N 2533/50 (2013.01);
Abstract

Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.


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