The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

Jul. 20, 2018
Applicants:

Neurolixis, Labruguiere, FR;

Uniwersytet Jagiellonski Collegium Medicum, Cracow, PL;

Inventors:

Anna Wesolowska, Cracow, PL;

Magdalena Jastrzebska-Wiesek, Cracow, PL;

Adrian Newman-Tancredi, Castres, FR;

Mark Andrew Varney, Dana Point, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A61P 25/08 (2006.01); A61K 9/00 (2006.01); A61K 31/135 (2006.01); A61K 31/428 (2006.01); A61K 31/4418 (2006.01); A61K 31/4433 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 9/0053 (2013.01); A61K 31/135 (2013.01); A61K 31/428 (2013.01); A61K 31/4418 (2013.01); A61K 31/4433 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61P 25/08 (2018.01);
Abstract

The present invention relates to the reduction of the side-effects induced by tetrabenazine or other inhibitors of vesicular monoamine transporter (VMAT), in the treatment of central nervous system disorders such as Huntington's disease, L-DOPA-induced dyskinesias in Parkinson's disease, Tourette's syndrome or tardive dyskinesia. The invention comprises administering to a patient in need thereof an effective amount of activates selective serotonin 5-HTreceptors agonist, whereby the side-effects of depression or Parkinsonism induced by tetrabenazine or other VMAT inhibitors are minimized.


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