The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2021

Filed:

Feb. 28, 2017
Applicant:

National Center of Neurology and Psychiatry, Tokyo, JP;

Inventors:

Takashi Okada, Tokyo, JP;

Shin'ichi Takeda, Tokyo, JP;

Hiromi Kinoh, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/76 (2015.01); A61K 48/00 (2006.01); A61K 38/17 (2006.01); A61K 9/51 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 9/14 (2006.01); A61K 47/42 (2017.01); C12N 5/00 (2006.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5184 (2013.01); A61K 9/14 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/42 (2013.01); A61K 48/0008 (2013.01); A61K 48/0091 (2013.01); C12N 5/00 (2013.01); C12N 7/00 (2013.01); C12N 15/113 (2013.01); A61K 47/26 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2510/02 (2013.01); C12N 2710/10042 (2013.01); C12N 2750/00042 (2013.01); C12N 2750/00051 (2013.01); C12N 2750/14142 (2013.01);
Abstract

An object of the present invention is to develop and provide a method for conveniently introducing a nucleic acid, a peptide, and/or a low-molecular-weight compound into an empty capsid with viral early infection activities kept. The present invention provides a method for producing a drug delivery particle, comprising the steps of: mixing an empty capsid or an empty particle with a drug including a nucleic acid, a peptide, and/or a low-molecular-weight compound in a solution comprising 0.1 to 20% of a surfactant; and keeping the obtained mixed solution at −5 to 50° C. to introduce the drug into the empty capsid or the empty particle.


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