The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Sep. 29, 2017
Applicant:

Genomictree, Inc., Daejeon, KR;

Inventors:

Sungwhan An, Daejeon, KR;

TaeJeong Oh, Daejeon, KR;

Assignee:

GENOMICTREE, INC., Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6806 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/16 (2013.01);
Abstract

The present disclosure relates to a method of detecting methylation of target DNA in a multiplex manner and a composition for detecting methylation of target DNA, and more particularly to a method for detecting methylation of target DNA, comprising: constructing an oligonucleotide, which comprises a target-specific sequence capable of binding complementarily to the target DNA and a universal primer that does not bind complementarily to the target DNA; linearly amplifying the target DNA for linear target enrichment by using the oligonucleotide as a primer; and amplifying the linearly amplified target DNA using an oligonucleotide, which is capable of binding complementarily to the linearly amplified target DNA, a universal primer, and a probe.


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