The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Jun. 04, 2020
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Hua Yu, Glendora, CA (US);
Andreas Herrmann, Pasadena, CA (US);
Marcin Tomasz Kortylewski, Monrovia, CA (US);
Assignee:
CITY OF HOPE, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); C12N 15/115 (2010.01); C12N 15/11 (2006.01); A61K 45/06 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); A61K 47/549 (2017.08); C12N 15/111 (2013.01); C12N 15/115 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/12 (2013.01); C12N 2310/13 (2013.01); C12N 2310/14 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3519 (2013.01); C12N 2320/30 (2013.01); C12N 2320/32 (2013.01);
Abstract
Provided herein are, inter alia, nucleic acid compounds useful for targeting CTLA-4-expressing cells and modulating cell activity of the CTLA-4-expressing cells. The compositions provided herein may be part of pharmaceutical compositions and may be used for treatment of cancer, inflammatory diseases, infectious diseases or metabolic diseases.