The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Jul. 31, 2015
Applicant:

The University of Western Australia, Nedlands, AU;

Inventors:

Willem Joost Lesterhuis, Nedlands, AU;

Richard Andrew Lake, Nedlands, AU;

Anthony Bosco, Subiaco, AU;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/203 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); A61K 31/21 (2006.01); C07K 16/28 (2006.01); G16B 5/00 (2019.01); G16B 20/00 (2019.01); A61K 31/34 (2006.01); A61K 45/06 (2006.01); A61K 31/445 (2006.01); A61K 31/495 (2006.01); G16B 20/20 (2019.01); A61K 31/198 (2006.01); A61K 31/216 (2006.01); A61K 31/382 (2006.01); A61K 31/409 (2006.01); A61K 31/4415 (2006.01); A61K 31/4468 (2006.01); A61K 31/453 (2006.01); A61K 31/506 (2006.01); A61K 31/551 (2006.01); A61K 31/58 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 31/198 (2013.01); A61K 31/203 (2013.01); A61K 31/21 (2013.01); A61K 31/216 (2013.01); A61K 31/34 (2013.01); A61K 31/382 (2013.01); A61K 31/409 (2013.01); A61K 31/445 (2013.01); A61K 31/4415 (2013.01); A61K 31/4468 (2013.01); A61K 31/453 (2013.01); A61K 31/495 (2013.01); A61K 31/506 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/58 (2013.01); A61K 38/1793 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2878 (2013.01); G16B 5/00 (2019.02); G16B 20/00 (2019.02); G16B 20/20 (2019.02); A61K 2039/505 (2013.01); A61K 2039/55 (2013.01); C07K 2317/76 (2013.01);
Abstract

This invention relates to systems and methods for evaluating the differentiality of a set of discrete random variables between two or more conditions, such as a malignant condition responding to treatment regime and one that is not. It also provides for the identification and selection of drugs that act in coordinated manner to phenocopy a genetic network of a malignant condition that responds to at least an immune checkpoint blockade agent.


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