The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Jul. 25, 2018
Nanjing Sanhome Pharmaceutical Co., Ltd., Jiangsu, CN;
Yong Wang, Jiangsu, CN;
Liwen Zhao, Jiangsu, CN;
Yazhou Wang, Jiangsu, CN;
Xu Quan, Jiangsu, CN;
Chunhuan Jiang, Jiangsu, CN;
Hongyan Chen, Jiangsu, CN;
Menghua Chen, Jiangsu, CN;
Chao Li, Jiangsu, CN;
Yexin Liao, Jiangsu, CN;
Qi Liu, Jiangsu, CN;
Chen Wang, Jiangsu, CN;
Hai Wang, Jiangsu, CN;
Shengwei Yang, Jiangsu, CN;
Guochuang Zheng, Jiangsu, CN;
NANJING SANHOME PHARMACEUTICAL CO., LTD., Jiangsu, CN;
Abstract
Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.