The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Dec. 12, 2017
Applicant:

The Hong Kong University of Science and Technology, Hong Kong, CN;

Inventors:

Benzhong Tang, Hong Kong, CN;

Ji Qi, Hong Kong, CN;

Ming Chen, Hong Kong, CN;

Wei Qin, Hong Kong, CN;

Pengfei Zhang, Hong Kong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 49/00 (2006.01); C07D 241/24 (2006.01); C07D 285/14 (2006.01); C07D 417/14 (2006.01); C07D 487/02 (2006.01); C07D 513/02 (2006.01); C07D 517/02 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 49/0023 (2013.01); C07D 241/24 (2013.01); C07D 285/14 (2013.01); C07D 417/14 (2013.01); C07D 487/02 (2013.01); C07D 513/02 (2013.01); C07D 517/02 (2013.01);
Abstract

A compound comprises a donor and an acceptor, wherein at least one donor ('D') and at least one acceptor ('A') may be arranged in an order of D-A; D-A-D; A-D-A; D-D-A-D-D; A-A-D-A-A; D-A-D-A-D; and A-D-A-D-A. The compound may be selected from the group consisting of: MTPE-TP, MTPE-TT, TPE-TPA-TT, PTZ-BT-TPA, NPB-TQ, TPE-TQ-A, MTPE-BTSe, DCDPP-2TPA, DCDPP-2TPA4M, DCDP-2TPA, DCDP-2TPA4M, TTS, ROpen-DTE-TPECM, and RClosed-DTE-TPECM. The compound may be used as a probe and may be functionalized with special targeted groups to image biological species. As non-limiting examples, the compound may be used in cellular cytoplasms or tissue imaging, blood vessel imaging, in vivo fluorescence imaging, brain vascular imaging, sentinel lymph node mapping, and tumor imaging, and the compound may be used as a photoacoustic agent.


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