The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Feb. 01, 2019
Applicants:
Univerzita Palackeho V Olomouci, Olomouc, CZ;
Ustav Experimentalni Botaniky Av Cr, V.v.i., Praha-Lysolaje, CZ;
Inventors:
Libor Havlicek, Krc, CZ;
Antonin Sturc, Modrany, CZ;
Eva Reznickova, Nova Ulice, CZ;
Radek Jorda, Neredin, CZ;
Vladimir Krystof, Olomouc, CZ;
Miroslav Strnad, Neredin, CZ;
Assignees:
UNIVERZITA PALACKEHO V OLOMOUCI, Olomouc, CZ;
USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I., Praha-Lysolaje, CZ;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01);
Abstract
5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidine derivatives of formula I that are effective inhibitors of kinases and exhibit strong antiproliferative and proapoptotic properties on lymphoma cells. Derivatives in the treatment of blood hyperproliferative diseases, such as Non-Hodgkin lymphomas are also disclosed.