The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Jun. 04, 2019
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Craig J. Thomas, Gaithersburg, MD (US);
Patrick Joseph Morris, Laurel, MD (US);
Richard Andrew Castledine, Northumberland, GB;
Samuel Lawrence Bourne, Northumberland, GB;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 221/00 (2006.01); C07C 249/02 (2006.01); C07F 7/18 (2006.01); C07C 269/04 (2006.01);
U.S. Cl.
CPC ...
C07C 221/00 (2013.01); C07C 249/02 (2013.01); C07C 269/04 (2013.01); C07F 7/188 (2013.01); C07B 2200/13 (2013.01);
Abstract
A process for the preparation of (2R,6R)-hydroxynorketamine is provided. The process requires no chromatography purification and affords the (2R,6R)-hydroxynorketamine in eight steps with a 26% overall yield and greater than 97% purity.